摘要
应用多普勒超声法测定了拉萨市15名健康男性世居藏族和11名健康男性移居汉族静息时的颈内动脉平均血流速度(ICAMFV);以了解高原居民运动时ICAMFV、脑血流(CBF)和脑氧供应量的状况。结果表明:静息时两组ICAMFV、CBF及脑氧供应量相似;次极量运动时,两组的ICAMFV和脑氧供应量均增加;但在最大运动负荷时,仅世居组的ICAMFV及脑氧供应量增加。ICAMFV的增加可代偿最大运动时因SaO2降低所致的脑氧供应量下降。最大运动时世居组的脑氧供应量高于移居组,主要以CBF增加同时与维持较高的SaO2有关。脑氧供应量的增加可能与提高最大运动负荷能力有关。结果说明长期居住于高原的世居人和移居人运动时CBF反应己恢复到与平原相似的正常状态。
Fifteen
male Tibetan native healthy residents versus ll acclimatized healthy male Hans ofLhasa(alt=3
658 m, PB=52.3 kPa)were studied to determine whether the cerebral blood flowincreased during
exercise. The Tibetans and Hans were matched for age,body size, resting
bloodpressure,hemoglobin concentration, and diameter of the internal carotid
artery.NoninvasiveDoppler ultrasonograph was used to measure internal carotid arterial mean
flow velocity(ICAMFV) and to assess cerebral blood flow(CBF) and cerebral O2 delivery.ICAMFV
and cer-ebral O2 delivery were similar in the two groups at rest.The ICAMFVand cerebral O2
deliveryincreased in Tibetan and Han groups during submaximal exercise workload.At maximal
efforts,the Tibetan retained the increase in ICAM FV and cerebral O2 delivery but the Han did
not.Greater cerebral O2 delivery was associated with increased maximal exercise performance
in theTibetan as compared with the Han group. The findings suggest that the CBF response to
exerciseis restored to nearly normal after long─term residence at high altitude.
出处
《中国应用生理学杂志》
CAS
CSCD
1994年第1期59-62,共4页
Chinese Journal of Applied Physiology
关键词
脑
血液流动
高原
低氧
运动
cerebral blood flow
cerebral O2 delivery
Doppler ultrasonograph
altitude hypoxia