摘要
目的对临床诊断为男性不育症患者进行染色体核型分析,探讨男性不育症与染色体之间的关系。方法采外周血淋巴细胞常规培养,Giemsa染色,显微镜下观察并分析染色体核型。结果对男性不育患者200例进行染色体核型分析,共发现59例异常,检出率29.50%。性染色体异常最多,并以克氏征(Klinefelter'ssyndrome)为主,共31例,占全部病例的15.50%。常染色体异常8例,检出率4.00%。结论染色体异常,尤其是性染色体异常是造成男性不育的重要原因。
[Objective]Objectives] To analyze chromosomal abnormality on male infertility, and to study the relations between chromosomal abnormality and male infertility. [Methods] Lymphocytes were cultured from peripheral blood of patients with male infertility,and then the chromosomes were analyzed. [Results] Of 200 cases of male infertility analysed, 59 cases were chromosomal abnormalities(29.5%). Sexual chromosome abnormalities were most commen, 31 cases of them were Klinefelter's syndrome(15.50%); 8 cases were autosome abnormalities(4.00%). [Conclusions] Chromosomal abnormalities, especially sexual chromosome abnormalities, are important cause of male infertility.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2005年第8期1239-1241,共3页
China Journal of Modern Medicine
关键词
男性不育
染色体
异常核型
male infertility
chromosome
abnormal karyotype