通心络胶囊治疗不稳定型心绞痛的临床效果观察

Clinical Observation of Curative Effect of Tongxinluo Capsule of Unstable Angina Pectoris

目的:探讨通心络胶囊治疗不稳定型心绞痛的临床疗效。方法:将60例不稳定型心绞痛患者配对后随机分为2组,对照组给予常规药物治疗,治疗组给予常规药物加通心络胶囊治疗,疗程为8周。通过观察2组患者治疗后血清C反应蛋白、血液流变学的变化及心绞痛发作情况评价疗效。结果:疗程结束后,治疗组血清C反应蛋白及血液流变学指标明显降低(P<0.01),对照组血液流变学指标也有明显改善(P<0.05),治疗组疗程结束后血清C反应蛋白、血液流变学指标及心绞痛发作改善情况与对照组比较,有显著性差异(P<0.01,P<0.05)。结论:通心络胶囊可以降低血清C反应蛋白及血液粘滞性水平,从而改善心肌缺血,是治疗不稳定型心绞痛的有效药物。

Objective:To investigate the therapeutic effect of Tongxinluo for unstable angina pectoris. Methods: 60 patients with unstable angina pectoris were randomly divided into two groups. The control group(30cases)was treated with routine therapy,and the treatment group (30cases)was treated with Tongxinluo capsule combined with routine therapy. A treatment course was 8 weeks for both groups. The C reactive protein (CRP) level and Hemorrheology before and after treatment were observed in both groups, and the angina pectoris of patients was observed for 8 weeks. Results: After treatment, CRP level and Hemorrheology in treatment group were increased significantly (P<0.01), and Hemorrheology in control group was increased significantly,too (P<0.05). There were significant differences in CRP level,Hemorrheology and angina pectoris between treatment group and control group after treatment (P<0.01, P<0.05). Conclusion: Tongxinluo capsule can decrease CRP level and the viscosity of blood and improve myocardial ischemia. So it is an effective drug for treating unstable angina pectoris disease.