艾滋病并发隐球菌脑膜炎15例临床分析

The clinical analysis of 15 cases of cryptococcal meningitis with AIDS

目的 分析艾滋病并发隐球菌脑膜炎临床特征、诊断方法。 方法 在临床表现、诊断方面就作者在非洲工作 2年间,收治的艾滋病并发隐球菌脑膜炎病人15例进行回顾性分析。 结果 所有病人均有发热、神经系统症状如:头痛、惊厥等。不同程度存在艾滋病相关表现。全部病例HIV,CSF墨汁染色法查隐球菌均阳性。 结论 艾滋病并发隐球菌脑膜炎临床表现没有特异性,目前脑脊液墨汁染色法,仍不失为简单、可靠的手段。血隐球菌多糖夹膜抗原测定,具有较高诊断价值。

Objective The aim of this paper is to summarise the clinical manifestations, dignostic procedures of cryptococcal meningitis with AIDS. Methods We retrospectively analyse 15 cases of cryptococcal meningitis with AIDS. Results All the patients had symptoms of fever, headache or convulsion. More or less,they had manifestations of AIDS. HIV were positive in all cases, as well as the ink stain of CSF. Conclusion The clinical manifestations are nospecific, cryptococcal meningitis may be easily dignosed by CSF ink stain, as well as by the detection of the cryptococcal capsular polysaccharide antigen in the blood