尿道神经纤维肉瘤的诊治

Diagnosis and Treatment of Urinary Neurofibrosarcoma

目的:探讨尿道神经纤维肉瘤的临床特点、诊断及治疗。方法:回顾性分析1例尿道神经纤维肉瘤患者的临床资料,结合文献复习。患者,男,61岁,10个月前曾行经尿道前列腺切除术,并经病理报告证实为良性前列腺增生。结果:患者行全尿道切除+全膀胱切除+回肠代膀胱术,术中见尿道前列腺部鱼肉胶冻样肿瘤组织伴大量陈旧性血凝块,病理报告为尿道神经纤维肉瘤侵犯膀胱,术后1月再发直肠肿块行二次手术,术中发现腹腔广泛转移,行横结肠造瘘术,术后进行性恶液质,40d后死亡。结论:对于尿道神经纤维肉瘤的术前确诊较为困难;该病恶性程度高,其治疗方法有待进一步探讨。

Objective: To investigate the clinical characteristics, diagnosis and treatment of urinary neurofibrosarcoma. Methods: Clinical data of 1 case of urinary neurofibrosarcoma was analyzed retrospectively and related literature reviewed. The 61-year old male patient had undergone TURP for benign prostate hyperplasia ten months before. Results: Total urethral cavernostomy, total cystectomy and ileal cystostomy were performed on the patient and pathological diagnosis pointed to urinary neurofibrosarcoma. Another operation was done for metastatic rectal mass, which revealed abdominal metastasis. With progressing consumptive constitution, the patient died 40 days after the second operation. Conclusion: It is difficult to make a definite diagnosis in urinary neurofibrosarcoma, and the effective treatment for this highly malignant disease needs to be further studied.