期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

骨髓间充质干细胞治疗肝硬化的实验研究 被引量：3

Experimental research of treating liver cirrhosis by transplanting bone marrow mesenchymal stem cells in rats
下载PDF
导出
作者 王豪勋 段芳龄 马军 梅雪 程香普 郑鹏远 唐芙爱
机构地区 郑州大学消化疾病研究所 河南中医学院病原学与免疫学教研室
出处 《胃肠病学和肝病学杂志》 CAS 2005年第3期277-278,共2页 Chinese Journal of Gastroenterology and Hepatology
基金 郑州大学"十五""211工程"重点学科建设项目 教重办(2002)第二号
关键词 干细胞治疗 骨髓间充质 实验研究 肝硬化 “横向分化” 多向分化潜能 间充质干细胞 组织细胞分化 肝细胞样细胞 cells 神经外胚层 自我更新 中胚层 Bone marrow Mesenchymalstem cells Transplant Li ver Cirrhosis
分类号 R318.04 [医药卫生—生物医学工程] R336 [医药卫生—人体生理学]
  • 相关文献

参考文献10

  • 1Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stemcell lines derived from human blastocysts, Science, 1998,282(5391 ): 1145-1147.
  • 2Prockop DJ. Marrow stromal cells as stem cells for nonhematopoietic tissues.Science, 1997,276 (5309): 71-74.
  • 3Deng W, Obrocka M,Fischer I,et al. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cycliC AMP. Biochem Biophys Res Commun, 2001,282(1) :148-152.
  • 4王晓,段芳龄,高天慧,朱武凌,陈香宇,颜伏归,韩娜,李文晰,李蔚.人骨髓多能成体祖细胞的分离培养及向肝细胞样细胞分化的研究[J].胃肠病学和肝病学杂志,2003,12(2):148-151. 被引量：7
  • 5孙艳,段芳龄,陈香宇,孙嫣,李玉龙,曾艳丽,王豪勋.体外诱导人脐血间充质干细胞向肝细胞样细胞分化的研究[J].胃肠病学和肝病学杂志,2004,13(3):239-243. 被引量：27
  • 6孙嫣,段芳龄,陈香宇,孙艳,李玉龙,曾艳丽,王豪勋.人骨髓间充质干细胞体外分化为肝细胞样细胞[J].胃肠病学和肝病学杂志,2004,13(3):244-248. 被引量：24
  • 7Schwartz RE, Reyes M, Koodie L, et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin lnvest, 2002,109(10): 1291-1302.
  • 8Kushida T, Inaba M, Hisha H, et al. Crucial role of donorderived stromal cells in successful treatment for intractable autoimmue diseasein mrl/1pr mice by BMT via portal vein. Stem cells,2001,19:226-235.
  • 9Terada N, Hamazaki T, Oka M, et al. Bone marrow cells adopt the phenotype of other cellS by cell fusion. Nature, 2002,416(6880): 542-545.
  • 10Ying QL, Nichols J, Evans EP, et al. Changing potency by spontaneous fusion. Nature, 2002,416(6880): 545-548.

二级参考文献22

  • 1[9]Avital I, Inderbitzin D, Aoki T, et al. Isolation, characterization, and transplantation of bone marrow-derived hepatocyte stem cells. Biochem Biophys Res Commun,2001,288( 1 ): 156-164.
  • 2[1]Reyes M, Verfaillie CM. Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells. Ann NY Acad Sci,2001, 938:231-235.
  • 3[2]Reyes M, Lund T, Lenvik T, et al. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood, 2001,98 ( 9 ):2615-2625.
  • 4[3]Wennerberg AE, Nalesnik MA, Coleman WB. Hepatocyte paraffin 1: a monoclonal antibody that reacts with hepatocytes and can be used for differential diagnosis of hepatic tumors. Am J Pathol, 1993,143(4): 1050-1054.
  • 5[4]Petersen BE, Bowen WC, Patrene KD, et al. Bone marrow as a potential source of hepatic oval cells. Science, 1999,284(5417): 1168-1170.
  • 6[5]Theise ND,Badve S, Saxena R, et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology,2000,31 ( 1 ): 235-240.
  • 7[6]Krause DS. Theise ND, Collector MI, et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell, 2001,105 ( 3 ):369-377.
  • 8[7]Wang X,AL-Dhalimy M, Lagasse E, et al. Liver repopulation and correction of metabolic liver disease by transplanted adult mouse pancreatic cells.Am J Pathol,2001,158(2) :571-579.
  • 9[8]Lagasse E,Connors H, AL-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med, 2000, 6 ( 11 ):1229-1234.
  • 10Anderson DJ,Gage FH,Weissman IL,et al.Can stem cells cross lineage boundaries? Nature Med,2001,7:393-395.

共引文献50

同被引文献21

  • 1姚鹏,王帅,胡大荣,闻炜,周一鸣,龚丽娟.肝动脉自体骨髓干细胞移植治疗失代偿期肝硬化30例[J].世界华人消化杂志,2005,13(13):1639-1640. 被引量：74
  • 2王豪勋,马军,段芳龄,程香普,梅雪,唐芙爱,郑鹏远,薛乐勋.骨髓间充质干细胞治疗肝硬化的动物实验研究[J].胃肠病学和肝病学杂志,2006,15(4):365-368. 被引量：15
  • 3Cantz T, Sharma AD, Jochheim-Richter A, et al. Revaluation of bone marrow-derived cells as a source for hepatocyte regeneration [ J ]. Cell Transplant, 2004, 13(6) :659-666.
  • 4Yannaki E, Athanasiou E, Xagorari A, et al. G-CSF.primed hematopoietic stem cells or G-CSF per se accelerate recovery end improve survival after liver injury, predominantly by promoting endogenous repair programs[J]. Exp Hematol, 2005, 33( 1 ) :108-119.
  • 5Luk JM, Wang PP, Lee CK, et al. Hepatio potential of bone marrow stromal cells;development of in vitro oo-culture and intra-portal trans- plantation models[J]. J Immunol Methods, 2005, 305 ( 1 ) :39-47.
  • 6Yamazaki S, Miki K, Hasegawa K, et al. Sera from liver failure patients and a demethylating agent stimulate transdiffemntiation of coculture with nonparenchymal liver cells[ J].J Hepatol, 2003, 39( 1 ) :17-23.
  • 7Okumoto K, Saito T, Hattorl E, et al. Differentiation of bone marrow cells into ceils that express liver-specific genes in vitro: implication of the Notch signals in differentiation [ J ]. Biochem Biophys Res Commun, 2003, 304(4) : 691-695.
  • 8Fang B, Shi M, Liao L, et al. Systemic infusion of FLK1 ( + ) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice[J]. Transplantation, 2004, 78(1) :83-88.
  • 9Teratani T, Yamamoto H, Aoyagi K, et al. Direct hepatic fate specification from mouse embryonic stem cells [ J ]. Hepatology, 2005, 41 (4) : 836-846.
  • 10Avital I, Inderbitzin D, Aoki T, et al. Isolation, characterization, and transplantation of bone marrow-derived hepatocyte stem cells [J]. Biochem Biophys Res Commun, 2001,288( 1 ) :156-164.

引证文献3

二级引证文献5

胃肠病学和肝病学杂志
2005年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部