脾阴虚证与血浆胃动素水平关系初探

Study on Motilin and Spleen-Yin Deficiency

对４４例脾阴虚患者的血浆胃动素水平进行了初步观察，并与脾气虚组、健康组进行对照。用自制的慎柔养真汤口服液对脾阴虚患者进行治疗观察。结果发现脾阴虚患者的血浆胃动素水平比健康组显著升高（Ｐ＜０．０１），但显著低于脾气虚组（Ｐ＜０．０１）。３组间总变异有显著性意义（Ｐ＜０．０１）。脾阴虚组、脾气虚组的血浆胃动素异常阳性率分别为６５．９１％、７５．００％。推测脾阴虚患者血浆胃动素水平升高与迷走神经兴奋性增高、胃肠道内环境受损，消化、吸收功能低下有关。

The Plasma motilin level in 44 cases patients with Spleen-Yin deficiency(SYD)was observed and compared with Spleen-Qi lnsufficiency(SQI),the normal control group.SYD patients were treated using selfmade Shen Rou Yang Zhen Tang oral liquor.The results showed that plasma motilin level was higher significantly than that of the control group(P<0.01),but was remarkably lower than that of SQI.The difference was significant among the three groups(P<0.01).The abnormal incidence of positive plasma motilin was 65.91% and 75.00% respectively.It is conjectured that the plasma motilin level in SYD was related to excitability of vagus nerve, disturbance of gastro-intestinal internal environment,indigestion and malabsorption of GI tract.