期刊文献+

健康老年人血瘀证的调查及血浆t-PA、PAI活性的研究 被引量:9

Epidemiological Study of Blood Stasis and Plasma Tissue Plasminogen Activator and Its Inhibitor Activity in Healthy Aged
下载PDF
导出
摘要 通过对77例健康老年人进行血瘀证的调查,并与35例健康青年人作对照,结果发现51.79%的健康人群有血瘀证出现,不同年龄组血瘀证检出率有非常显著性差异(P<0.005)。同时随年龄增长,血瘀证检出率呈递增变化规律。采用发色底物分析法检测血浆组织型纤溶酶原激活剂(t-PA)及其抑制物(PAI)的活性及P/t比值。结果显示:老年前期及老年期血浆t-PA活性均明显高于青年人(P均<0.01)。而PAI活性各年龄组均无显著差异,P/t比值老年人显著下降(P<0.05)。实为老年机体对抗高凝状态的生理代偿反应,对促使老年人维持生理平衡有极其重要的意义。 According to the blood stasis survey of 77 healthy subjects in presenile geriatric period, in comparison with 35 healthy young people, it was found the 51.79% of healty subjects had blood stasis. The detectable rate were significantly different among various age groups(P<0.005), and the rate increase was age-dependent. Chromogenic peptide substrate analytical method was used to detect plasma tissue plasminogen activator(t-PA), tissue plasminogen activator inhibitor (PAI) activity and ratio of P/t. The result revealed that the activity of plasma t-PA in presenile geriatric perlod subjects was significantly higher than that of young people(P< 0.01). but the activity of PAI had no difference in various age groups, and the ratio of P/t was markedly decreased. It showed that this was the physiological compensatory reaction of aging organism against hypercoagulability, and it was an effective way to maintain the physiological balance of the aged.
出处 《中国中西医结合杂志》 CAS CSCD 北大核心 1994年第12期721-723,共3页 Chinese Journal of Integrated Traditional and Western Medicine
基金 福建中医药中西医结合科研基金
关键词 老年人 血瘀证 T-PA PAI 血浆 调查 aging, blood stasis, tissue-type plasminogen activator, plasminogen activator iuhibitor
  • 相关文献

参考文献1

同被引文献96

引证文献9

二级引证文献64

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部