当归补血汤补血作用机理的探讨

Research on the Mechanism of Blood-tonifying Effect of Danggui Buxue Decoction

当归补血汤能显著促进正常小鼠ＳＣＭ，ＬＣＭ中，及血虚小鼠ＳＣＭ中ＣＳＦｓ的产生。当归促进，而黄芪显著抑制正常小鼠ＳＣＭ中ＣＳＦｓ生成。结果揭示当归补血汤的补血活血作用与其刺激ＣＳＦｓ分泌有关，且系当归的作用所致。

anggui Buxue Decoction has shown the effects of significantly promoting the splenic capacity of healthy mice in generating cloe-stimilating factors(CSFs)both in spleen conditioned medium(SCM)and in lung conditioned medium(LCM),and markedly enhancing the capacity of the lungs of blood-deficient mice in generating CSFs in spleen conditioned medium. CSFs generation in SCM is promoted in the spleen of healthy mice given Angelica sinensis, but markedly inhibited if Astragulus menbranacous is used.The results suggest that blood-tonifying and blood-activating effects of Danggui Bu xue Decoction are associated with its CSFs secretion-stimulating action,which is brought about by Angelica simensis.