逐瘀泄热开闭合剂治疗流行性出血热休克32例疗效及血浆β-内啡呔含量的观察

Observations on Curative effect and the Content of Plasma β-Endorphin in 32 Cases of EHF in Shock Treated with Compound Decoction for Removing Stasis, Expelling Heat and Inducing Resuscitation

本文报道以中医辨证论治为依据、采用逐瘀泄热开闭合剂,配合参麦针的开闭固脱疗法,辨治流行性出血热(EHF)休克32例,并与西医对照组 22例进行对比观察;同时对其中48例EHF休克患者治疗前后血浆β-内啡呔%(β-EP)的含量变化进行了检测.结果治疗组总有效率96.88%,对照组总有效率95.45%,无显著性差异.在临床观察中发现,与对照组相比,治疗组休克纠正时间短,血浆β-EP含量复常快,病情缓解明显.作者认为采用逐瘀泄热开闭合剂配合参麦针的开闭固脱法是提高EHF休克抢救成功率的关键.

According to TCM theory,we treated 32 cases of EFH in shock with compound decoction for removing stasis ,expelling heat and inducing resuscitation, together with combined use of injection of Ginseng and Ophiopogonis for restoring consciousness and resolving cold. Another 22 cases of EHF in shock treated with Western medicine served as control group. In 48 cases,the content of plasma β-endorphin was measured before and after treatment. The results showed that the overall effective rate was 96. 88% in treated group while that in the control group was 95. 45%. There was no statistically significant difference between the two groups. Compared with control group, the treated group took a shorter time to step-up the blood pressure and correct the content of β-endorphin to normal level, and the general condition of the patients was improved more markedly and rapidly. All these suggested that this compound liquor for removing stasis,expelling heat and inducing resuscitation with combined" use of injection of Ginseng and Ophiopogonis for restoring consciousness and resolving cold was the key therapy to increase the survival rate of EHF in shock.