急性胰腺炎患者CRP和IL—6水平检测及临床意义

Clinical Significance of Detecting C-Reactive Protein and IL-6 on Patients with Acute Pancreatitis

目的:C-反应蛋白和IL-6测定在诊断轻、重型胰腺炎患者中的临床应用价值。方法:血清CRP测定采用快速比浊法,IL-6测定采用双抗体夹心ELISA法。结果:重型胰腺炎患者CRP和IL-6水平显著高于轻型胰腺炎患者;显著高于正常健康对照组(P<0.01)。结论:CRP和IL-6水平测定可为早期诊断和区别轻、重型胰腺炎提供可靠的实验依据。

Objective: Evaluation the clinical significance of C-reaction protein(CRP) and IL-6 in diagnosis of severe and mild pancreatitis. Methods: To mensurate serum CRP and IL-6 by kinetic turbidimetric test and double antibodies sandwich ELISA respectively. Results:The levels of serum CRP and IL-6 are higher in the patients of severe pancreatitis than the mild and health control group(P<0.01). Conclusions: Measure of serum CRP and IL-6 can be used as credible experiment data in diagnoses of severe and mild pancreatitis.