胃肠道疾病与情绪障碍的相关因素调查分析

Correlation factor in gastrointestinal disease and mood disorder

目的调查胃肠疾病与情绪障碍(Mooddisorder,MD)的相关因素。方法对1523例初次就诊、并明确诊断的胃肠疾病患者,予以Zung自评抑郁量表(SDS)和自评焦虑量表(SAS)评分;详细记录每位患者的性别、年龄、职业、学历、病程等相关因素,予以分析。结果胃肠疾病患者MD发生率为32.7%(498/1523)。功能性胃肠疾病MD发生率为41.6%,高于器质性胃肠疾病(23.4%)(P<0.001);前者SAS评分=62.40±7.65、SDS评分=58.43±6.63,均高于后者(SAS评分=58.41±5.90、SDS评分=55.29±5.78)(P<0.001)。女性MD发生率为35.9%,高于男性(28.9%)(P<0.01);女性SAS评分=61.85±7.71、SDS评分=57.88±6.52,均高于男性(SAS评分=59.79±6.57、SDS评分=55.87±5.89)(P<0.01～0.05)。不同年龄、职业、学历、病程的患者MD发生率不同(P<0.001～0.05);年龄以31～60岁者好发,但男性更多在青年期、女性更多在中年期好发;职业以私营业主(含商人)、学历以高中以上(含高中)者好发;病程方面,功能性胃肠疾病3年以上较3年以下、器质性胃肠疾病12月以上较12月以下者MD发生率高、程度重(P<0.05)。结论胃肠疾病中有较高的MD发生率,MD的发生与患者疾病、性别、年龄、职业、学历、病程等多种因素相关。

Objective To investigate correlation factor in gastrointestinal disease (GID) and mood disorder (MD). Methods To analyze the psychological status of 1523 GID outpatients, who visited the gastrointestinal specialist for the first time by using Zung's self-rating depression scale (SDS) and Zung's self-rating anxiety scale (SAS). Analyze their gender, age, occupation, educational background , course of disease and other relative factors. Results The prevalence of MD in GID was 32.7%(498/1523), in functional dyspepsia was 41.6%, both were higher than in organic GID(23.4%),(P<0.001); In functional dyspepsia SAS score was 62.40±7.62, SDS score was 58.43±6.63, both higher than in GID, in which SAS score was 58.41±5.90, SDS score was 55.29±(5.78,(P<0.001). The prevalence of MD in female was 35.9%, higher than in male's (28.9%) (P<0.01); The SAS and SDS score in female were 61.85±7.71,57.88±6.52 respectively, both were higher than in male's, which were 59.79±6.57and 55.87±(5.89(P<0.01～0.05). There was different MD incidence according to age, occupation, educational background and course of disease(P<0.001～0.05). Those who were 31 to 60 years old ,who were merchant, private proprietor, or with a more than senior high school academic career had a high risk. Males tended to have MD in adolescence while females in middle-age. As for course of disease, patients having functional dyspepsia more than 3 years , havingorganic GID more than 12 months were easy to get MD, and the MD symptom were more serious(P<0.05).Conclusion The prevalence rate of MD is higher in GID, and is relative to patients' gender, age, occupation, educational background and course of disease etc.