针灸治疗失眠症随机对照试验的系统评价

A systematic evaluation of randomized controlled trials for acupuncture and moxibustion treatment of insomnia

目的 :评价针灸治疗失眠症的疗效。方法 :对针灸治疗失眠症的随机对照试验 (RCT)进行系统评价。统计方法数据用专用软件RevMan4 1版进行统计分析。结果 :6篇RCT共 5 85例患者满足纳入标准。 6篇均为低质量试验 ,均未使用盲法 ;Meta 分析的结果 ,针刺组和药物组比较 ,比值比 (OR)为 3 5 5 ,95 %的可信区间 [2 5 0 ,5 0 5 ],P <0 0 0 0 1。结论 :针灸治疗失眠症可能有效 ,但由于试验方法学质量较低 ,尚不能充分肯定 ,需高质量的试验进一步证实。

Objective To assess the therapeutic effect of acupuncture on insomnia. Methods A systematic evaluation of all relevant randomized controlled trials (RCT) about acupuncture and moxibustion treatment of insomnia was carried out. The data were statistically analyzed with a special software RevMan 4 1. Results Six papers of RCT including 585 patients met the enrolled criteria. All of the trials were of lower in methodological quality without using blind method; Meta analysis indicated that odds ratio was 3 55,95% confidence interval [2 50,5 05], P <0 0001,as acupuncture group compared with drug group. Conclusion Acupuncture is possibly effective for insomnia. However, because of lower methodological quality of all the trials, this conclusion has no enough evidence.