醒脑开窍针法治疗卒中后抑郁症临床研究

Study on clinical therapeutic effect of activating brain and regaining consciousness needling method on poststroke depression and the mechanism

目的 :探讨治疗卒中后抑郁症的有效方法。方法 :随机将 2 5 6例卒中后抑郁症患者分为口服西药对照组 (76例 )和醒脑开窍针法针刺组 (180例 ) ,观察两组临床疗效 ;以卒中后抑郁症相关因素及血浆中相关单胺类神经递质含量的变化为指标探讨治疗机制。 结果 :针刺组患者的临床症状和各种抑郁量表相关指标均得到改善 ,血液中相关单胺类递质含量提高 ,与西药组比较差异有显著性意义 (P <0 0 5 )。结论 :醒脑开窍针法可以通过改善疾病相关因素来治疗卒中后抑郁症。

Objective To probe into an effective method for treatment of poststroke depression. Methods Two hundred and fifty six cases of poststroke depression were randomly divided into a control group ( n =76) treated by oral administration of amitilin and an acupuncture group ( n =180) treated by activating brain and regaining consciousness needling method. Their clinical therapeutic effects and changes of relative factors of poststroke depression and plasma contents of monoamine neurotransmitters were observed. Results In the acupuncture group, the clinical symptoms and the relative indexes in the depression scales improved and plasma contents of the monoamine neurotransmitters increased significanty as compared with the control group ( P <0 05). Conclusion The needling method for activating brain and regaining consciousness can improve relative factors to cure poststroke depression.