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子宫内膜异位症恶变的研究进展 被引量:3

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摘要 子宫内膜异位症(EMs)是妇科多发病,虽是一种良性疾病,但有恶性生物学行为。研究表明有一定比例的EMs发生组织学改变,成为癌瘤。EMs与子宫内膜样卵巢癌和透明细胞卵巢腺癌的同步发生率较高,其病灶细胞可发生基因缺失、基因突变、杂合性丢失和染色体倍数异常等改变。激素抑制治疗可能未改善EMs患者的健康状况,相反,可能增加其恶变率。综述EMs恶变在临床、遗传学、治疗方面的进展。
出处 《国外医学(妇产科学分册)》 2005年第3期173-176,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
基金 国家自然基金资助项目(编号:30471805)
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