围手术期输血对结肠癌根治术后复发率影响

Adverse Effect of Perioperative Blood Transfusion by Augmenting Risk of Recurrence after Curative Resection of Colonic Cancer

作者对129例结肠癌根治术后复发率进行回顾性总结.发现围手术期输血确能增高结肠癌根治术后复发率.输血组复发率为29.14％,未输血组复发率为零.二组数字有显著性差异.输血能增高结肠癌根治术后复发率的机理是宿主免疫系统的抑制.作者建议结肠癌根治术一般情况下应不输血.

Retrospective study of 119 patients who received blood transfusion Eerioperatively during colectomy in comparison with 10 patients who had no transfusion. Recurrence rate for the transfused group was 29. 41 % ,and 0% for the non-transfused group. This difference was highly significant statistically (P<0. 05). The authors conclude that perioperative blood transfusions produce a significant detrimental effect on patients who undergo curative resection for colonic cancer.