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腹膜透析中超滤衰竭的治疗体会 被引量:2

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摘要 目的:探讨腹膜透析中并发超滤衰竭的防治对策。方法:回顾性总结3例腹膜透析中超滤衰竭患者使用7.5 %葡聚糖(Icodextrin)腹透液进行连续性不卧床腹膜透析(CAPD)治疗,并配合使用1.5 % (或4 .2 5 % )葡萄糖腹透液,使病人恢复超滤,保持每天超滤10 0 0~15 0 0ml。结果:病人水肿都消失,症状好转,观察1~15个月,病情稳定,复查各项生化参数稳定。结论:腹膜透析中超滤衰竭的防治对策:(1)腹膜透析中并发超滤衰竭的原因还不清楚,多于长期透析后出现,提示长时间是一个主要原因。(2 )腹膜透析中并发超滤衰竭时,暂停腹膜透析,临时转为血液透析,多数病人腹膜功能能够恢复,是有效治疗方法之一。(3)使用生物相容性好、超滤效果佳的新类型7.5 %葡聚糖腹透液进行CAPD治疗,葡聚糖分子量大(2 0 0 0 0d) ,葡聚糖腹透液可保持有效渗透压达16h ,超滤效果好,可以改变超滤衰竭病人的治疗效果。(4)在传统的葡萄糖腹透液中添加药物,以期保护腹膜,增加净超滤量。(5 )研制生物相容性更好的腹透液是预防腹膜超滤衰竭的关键因素。
出处 《中国中西医结合肾病杂志》 2005年第6期360-361,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 广东省汕头市科技计划项目 (No .2 0 0 43 3 )
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参考文献3

  • 1Heimburger O,Waniewski J,Werynski A, et al.Peritoneal transport in CAPD patient with permanent loss of ultrafiltration capacity.Kidney Int,1990,38(3):495-506.
  • 2孙玉玲,Susan Yung,余学清,梁国雄,曾志伟,陈德瑁.氨基酸腹膜透析液与传统腹膜透析液对腹膜间皮细胞功能的影响[J].中华肾脏病杂志,2004,20(1):37-41. 被引量:15
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二级参考文献1

共引文献14

同被引文献35

  • 1姚峥,贾强.连续不卧床腹膜透析超滤衰竭原因分析及对策[J].中国血液净化,2004,3(11):583-586. 被引量:1
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