颅内脑膜瘤复发因素的探讨

Factors Related to Recurrence of Intracranial Meningiomas

本文报道颅内脑膜瘤1289例,其中复发性脑膜瘤167例,复发率14.9％.内皮型脑膜瘤复发率高于纤维型和过渡型脑膜瘤,大脑凸面和侧脑室脑膜瘤的复发率最低,矢状窦旁、蝶骨嵴和眶内等部位脑膜瘤的复发率最高.脑膜瘤复发率高低除与肿瘤部位和手术切除级别直接有关外,与肿瘤的病理性质,生长方式以及多灶性生长有关.脑膜瘤有恶变趋势,良性脑膜瘤复发恶变率为25.2％,大脑凸面、矢状窦旁、大脑镰旁、中颅窝和小脑幕等部位脑膜瘤复发恶变率较高.

A report of 1289 cases of intracranial meningiomas was made of which 167 cases (14. 9 % ) were recurrent. Endotheliomatous meningiomas recurred more readily than those of fibroblastic and transitional types. The recurrence rate in parasagittal, sphenoid ridge and intraorbital meningiomas was the highest and that in intraventricular and cerebral convexity was the lowest. The recurrence rate of meningiomas correlated not only with the site of lesion and the operative magnitude,but also with the pathologic features,patterns of growth,and multicentricity. Meningiomas tend to undergo malignant change and may rate as high as 25. 2 % in case of recurrent meningiomas especially those in the cerebral convexity, parasagittal,falcial,middle fossa and tentorial areas.