Ⅰ期乳腺癌253例临床病理分析

Clinico-pathological Analysis of 253 Stage Ⅰ Breast Cancers

我院自1973年到1983年底共手术治疗253例Ⅰ期乳腺癌,占经治可手术女性乳腺癌2665例的9.5%.其中肿瘤≤0.5cm者15例,0.6cm^1cm者43例,1.1cm^2cm者195例.行传统根治术90例,改良根治术148例,全乳切除术11例和局部切除术4例.临床为N_0者病理检查18.6%见淋巴结转移,N1a者30.1%阳性.本组病例的10年健在率为79.4%.其中非浸润性癌、早期浸润性癌、浸润性特殊型癌及浸润性非特殊型癌10年健在率分别为92.7%、78.6%、96.8%及72.8%;原发癌≤0.5cm、0.6cm^1cm及1.1cm^2cm者的10年健在率分别为93.3%、81.4%及77.9%.治疗结果与术式无明显相关.

During the period of 1973-1983,253 patients with stage I breast cancer were treated by surgery. They accounted for 9.5% of 2665 cases of primary breast cancer treated at this hospital during the same period. In 15 cases,the tumor were≤0. 5 cm in diameter, 43 tumors were 0. 6cm-1. 0cm and 195 tumors were 1. 1cm-2.0cm. Halsted operation was done in 90 cases,modified radical mastectomy in 148,simple mas-tectomy in 11 and lumpectomy in 4 cases. Lymph node metastases were found in 18. 6% in No cases and 30.1% in Nla cases.The total clinical 10-year NED rate was 79. 4%. The 10-year NED rate of noninfiltrative carcinoma was 92. 7% .early infiltrative carcinoma was 78. 6% ,infiltrative specific carcinoma was 96. 8% and infiltrative nonspecific carcinoma was 72. 8%. The NED rate of the primary carcinoma ≤0. 5cm,0. 6cm-l. 0cm,and 1. 1cm-2. 0cm were 93. 3% ,81. 4% and 77. 9% respectively. No relation was found between the long term result and the type of operation.