肝动脉化疗栓塞术对患者生命体征的影响

Effect of transcatheter hepatic arterial chemoembolization on vital sings of patients

目的探讨经导管肝动脉化疗栓塞术(TACE)术中生命体征变化发生率,为预防TACE并发症提供依据。方法对220例因肝脏恶性肿瘤做首次TACE的患者进行了系统护理监测,观察TACE术中心电图、血压和呼吸等生命体征变化发生的频次,分析术中影响生命体征变化的因素。结果监测发现有统计学意义的生命体征变化的发生率为17.7%(39/220),发生于TACE开始后3～10min。其中心率减慢占16.6%,血压下降占12.7%,心率增快占3.2%,血压增高占3.6%。结论TACE术中患者生命体征变化的发生较多,有些改变(如心率减慢、血压下降)可能造成严重后果,需要加强护理观察及给予及时处理。

Objective To investigate the changes of vital signs during the transcatheter hepatic arterial chemoembolization (TACE) so as to prevent complications. Methods Systematically, monitoring of the vital signs was performed in 220 patients with hepatic malignant tumors during their first TACE procedures. Such vital signs as ECG, blood pressure and respiration were observed and the factors affecting vital signs were analyzed. Results In monitoring, the 17.7%(39/220) of the patients had significant changes of the vital signs at 3～10 min at the beginning of chemoembolization (P<0.01). Decrease of heart rate (HR) was observed in 16.6% and dramatic decrease of blood pressure in 12.7% of them. 3.2% of the patients had dramatic increases of HR and 3.6% had increase of BP. Conclusion During TACE, the vital signs change in the patients. Some changes like HR slowing down and BP dropping may result in poor outcomes and need to be treated in time.