静脉推注和静脉滴注葡萄糖酸钙不良反应比较及护理

The side effects of calcii gluconas in venous injection and venous infusion and the nursing care

目的探讨静脉推注和静脉滴注葡萄糖酸钙不同给药方法不良反应发生情况。方法对400例静脉应用葡萄糖酸钙病人,按就诊先后顺序随机分成两组,每组200例,静脉推注葡萄糖酸钙为静注组,静脉滴注葡萄糖酸钙为静滴组,观察病人头晕、头痛、恶心呕吐、胸闷、心前区不适、心律失常等不良反应发生情况。结果静滴组病人头晕、头痛、恶心呕吐、胸闷、心前区不适、心律失常等不良反应发生率明显少于静注组(P<0.05或P<0.01)。结论静脉滴注葡萄糖酸钙较静脉推注葡萄糖酸钙,在减少病人用药不良反应方面有显著的效果,且临床应用简便,值得推广。

Objective To investigate the side effects of calcii gluconas in venous injection and venous infusion. Methods 400 patients administrated with calcii gluconas were randomized into two groups equally: venous injection group and venous infusion group. The patients in both groups were observed in terms of dizziness, nausea, emesis, chest distress, upset in precordial region, and arrhythmia. Results The occurrence rate of side effects like dizziness, nausea, emesis, chest distress, upset in precordial region, and arrhythmia in venous infusion group was significantly lower than that of venous injection group (P<0.05 or P<0.01). Conclusion Administration of calcii gluconas by venous infusion is effective in reducing its side effect. It is simple in clinic and worth popularizing.