基因芯片技术在经脉脏腑相关研究中的应用思考

Thinking of application of gene chip technique in the study of channel-viscera correlativity

目的:探讨基因芯片技术在经脉脏腑相关研究中可能存在的应用思路及前景。方法:采用文献分析方法,回顾与分析基因芯片在生物学和医学领域中的应用现状及有关经脉脏腑相关研究成果。结果:基因芯片在生物学和医学领域中可应用于高通量基因表达平行分析、大规模基因发现及基因分析、基因多态性分析和基因组研究等,特别在表达谱中有重大应用价值;经脉脏腑相关研究须从多学科、多系统、多方位、多环节、多水平进行立体交叉研究,使之更具系统化、序贯化,而基因芯片技术应用特点可适应这一需求。结论:基因芯片技术的广泛应用将全面推动经脉脏腑相关研究工作的深入。

Objective To probe into thinking and prospect of application of gene chip technique to research of the channel-viscera correlativity. Methods Adopt literature analytic method, review and analyze current state of application of gene chip in biology and medicine, and achievements in studies of channel-viscera correlativity. Results In biological and medical fields, gene chip can be applied to high flux expression parallel analysis, large-scale gene discovery and gene analysis, gene polymorphous analysis, genome study, etc, especially, it has important application values in gene expression map; channel-viscera correlativity need stereo-crossing studies by multiple subjects, multiple systems, multiple directions and multiple levels, being more systematic and sequential, and gene chip technique is applicable to this requirement. Conclusion Wide application of gene chip technique will comprehensively promote deep study of channel-viscera correlativity.