针刺治疗单纯性肥胖症及其对患者血清瘦素的影响

Acupuncture for treatment of simple obesity and its effect on serum leptin level of the patient

目的:观察针刺减肥的疗效及探讨针刺减肥的作用原理。方法:将50例单纯性肥胖症患者随机分为针刺治疗组和药物对照组,每组各25例。针刺治疗组采用体针、电针配合耳穴贴压的方法(体穴取天枢、关元等,耳穴取神门、内分泌等);药物对照组采用口服西药西布曲明的方法。分别于治疗前后检测患者血清瘦素的含量,并评价减肥疗效。结果:针刺治疗组的总有效率为88.0%,药物对照组的总有效率为80.0%,两组的治疗结果相近(P>0.05);两组患者治疗后血清瘦素水平均较治疗前显著下降(P<0.01),且针刺治疗组下降水平优于药物对照组(P<0.05)。结论:针刺减肥的疗效确切,针刺能有效地改善单纯性肥胖症患者的高瘦素血症,这可能是针刺减肥的作用机理之一。

Objective To explore the therapeutic effect and the mechanism of acupuncture in reducing body weight. Methods Fifty cases of simple obesity were randomly divided into an acupuncture group and a drug control group, 25 cases in each group. The patients in the acupuncture group were treated with body acupuncture at Tianshu (ST 25), Guanyuan (CV 4), etc, electroacupuncture and ear point tapping and pressing therapy (Shenmen, Endocrine, etc. were selected); the patients in the control group were treated with oral administration of sibutra-mine. The serum leptin level before and after treatment were determined and the therapeutic effect in reducing body weight was assessed. Results The total effective rate was 88. 0% in the acupuncture group and 80. 0% in the control group, with no significant difference between the two groups (P>0. 05); after treatment, the serum leptin level in both the two groups decreased significantly (P<0. 01) , and the decreasing amplitude in the acupuncture group was superior to that in the control group (P<0. 05). Conclusion Acupuncture therapy has a definite therapeutic effect in reducing body weight, and the improvement of serum leptin level of the patient is possibly one of the mechanisms of acupuncture in reducing body weight.