穴位埋线对慢性胃炎患者环核苷酸及胃肠激素的影响

Effects of thread embedding therapy on nucleotides and gastrointestinal hormones in the patient of chronic gastritis

目的:观察穴位埋线治疗慢性胃炎的临床疗效。方法:将70例慢性胃炎患者随机分为埋线组(36例)与针刺组(34例)。主穴均为胃俞、中脘、足三里,分别进行埋线或针刺治疗,并观察血浆环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)含量及胃泌素(Gas)、P物质(SP)含量的改变。结果:埋线组总有效率为88.89%优于针刺组76.47%(P<0.05);两组各自治疗前后比较,血浆cAMP、cGMP、Gas、SP含量的改变差异具有非常显著性意义(P<0.01);埋线组各项指标的改善程度均优于针刺组(P<0.05)。结论:穴位埋线治疗慢性胃炎有肯定疗效,通过调节环核苷酸和胃肠激素含量,从而改善了神经-内分泌-免疫调节功能。

Objective To observe therapeutic effect of thread embedding therapy on chronic gastritis. Methods Seventy cases of chronic gastritis were randomly divided into the treatment group (n=36) treated by thread embedding therapy and the control group (n = 34) by acupuncture. Weishu (BL 21), Zhongwan (CV 12) and Zusanli (ST 36) were selected as main points. And plasma contents of cAMP, cGMP, gastrin and substance P were observed before and after treatment. Results The total effective rate was 88. 89% in the treatment group and 76. 47% in the control group with a significant difference between the two groups (P<0. 05); there were significant differences before and after treatment in plasma contents of cAMP, cGMP, gastrin and substance P in the two groups (P< 0. 01), and the changes of these indexes in the treatment group were significantly superior to the control group (P< 0. 05). Conclusion Thread embedding therapy has a definite therapeutic effect on chronic gastritis and it can adjust nucleotides, gastrin and substance P to improve the functions of the nerve-endocrine-immunity network.