不同形态饲料对慢性胃炎模型大鼠胃黏膜修复及胃组织结构的影响

Effect of Different Form Forage on Recovery of Gastric Mucosa and Gastric Histological Structure in Chronic Gastritis Model Rat

目的:观察不同形态饲料对慢性胃炎模型大鼠胃黏膜修复及胃组织结构的影响。方法:以胃液量、胃酸pH值、溃疡面积、胃黏膜表面pH值、腺管总长度、表面上皮长度、壁细胞计数等为指标评价。结果:干饲料组和流质饲料组的胃液量无明显差异(P>0.05),干饲料组胃液pH值、胃黏膜表面pH值却显著增高、酸性降低(P<0.05,P<0.01),溃疡面积也显著减小(P<0.01);干饲料组腺管总长度、表面上皮长度均增长、壁细胞计数增多(P<0.01)。结论:干饲料减轻了攻击因子对胃黏膜的刺激作用,抑制了炎症发展,有利于胃黏膜屏障修复和防御功能。

Objective:To study the effect of different form forage on recovery of gastric mucosa and histological structure.Methods:To analyse gastric juice,pH of gastric acid,ulcerative areas,pH of gastric mucosa surface,total length of cryptae,cell quanta of surface epithelium and parietal in chronic gastritis model rat.Results:The gastric juice in rat by feeding dry forage and fluid forage was not discrepant(P > 0.05).But in rat by feeding dry forage,pH of gastric juice and gastric mucosa surface significantly heightened,acor depressed(P < 0.05,P > 0.01),ulcerative area lessened as compared with fluid forage group(P > 0.05).For gastric histological structure,total length of cryptae,cell quanta of surface epithelium and parietal multiplication increased in rat by feeding dry forage as compared with fluid forage group.Conclusion:Dry forage relieves irritant action on attack factor for gastric mucosa,inhibits inflamed growth and facilitates for recovery and defense function of gastric mucosal barrier.