鸡胚胎软骨植入鸡关节软骨缺损区的研究

Homotransplantation of Primary Cultured Chondrocytes: An Experimental Study in Chick

将鸡胚胎软骨细胞植入胶原蛋白凝胶内，经体外培养７２小时后，植入鸡关节软骨缺损区，通过１６周大体观察、组织学及电镜观察，显示植入的软骨细胞生长、分化良好，植入物周围未见免疫排异反应。

Chondrocytes of enbryonal chicken were cultured within collagen gels for 3 dags and then were transplanted into full thickness defects in chick articular cartilage and followed up for sixteen weeks. The results showed that the defects were filled with hyaline cartilage in a smooth articular surface and an appearance similar to that of the recipient cartilage. The cells of the repaired tissue were arranged as observed in normal articular cartilage on histomorphology and electronograph. There was no histological evidence of immunological rejection.