住院肺炎患儿军团菌感染回顾性研究

RETROSPECTIVE EVALUATION OFLEGIONELLA PNEUMOPHILA INFECTIONS INHOSPITALIZED CHILDREN

对８４例肺炎患儿，采用间接免疫荧光技术进行嗜肺军团菌（Ｌｐ）感染监测，１２例确诊为Ｌｐ病，阳性率为１４．３％，Ｌｐ＿Ｉ、Ｌｐ＿（ＩＩＩ）及Ｌｐ＿（ＩＶ）各４例。双份血清恢复期抗体滴度较急性期增高４倍，达到１：１２８者４例；单份血清滴度１：２５６者５例，１：５１２者３例。Ｌｐ肺炎临床表现主要以发热、寒战、阵咳、喘憋、肺部湿暧音及叩浊为主。胸片示肺部均有不同浸润，以右下片影为主。全部病例采用红霉素治疗，效果明显。

Abstract In order to evaluate legionella pneumophila (LP)infection in pediatric cases, we carried out studies in 84cases aged 2￣12 years in one division of our liediatricdepartment using immunofluorescent antibody (IFA)technique from July, 1990 to December, 1992. The re-sults demonstrated that 12 cases were positlve for LPwith a positive rate of 14.28%; among whom 4,4 and 4were positive for antibody to types I, III and IV of LP,respectively. Main clinical manifestations included fe-ver, chill, pereistent cough, wheeze and rales, andpulmonary dullness. X-ray demonstrated in mostcases pulmonary infiltration, and in 4 cases large denseinfiltration. The total white blood cells andneutrophils increased in all cases. Erythromycins weregiven to all cases and significant theral)eutic effectswere obtained; the course of treatment was 7￣ 10days, longer in some cases.