24例颅底脊索瘤临床分析

Clinical Analysis of 24 Cases of Chordomas in the Skull Base

总结２４例颅底脊索瘤，介绍了患者的一般情况、临床表现、诊断治疗及随访情况。根据其症状、体征、影像学检查结果、手术所见及病变起源部位与扩展方向，分为四种临床类型：蝶鞍型、斜坡型、枕颞型和广泛型。并提出手术进路选择。从本组结果可以看出，颅底脊索瘤临床症状繁杂，又无特异性表现，加之其部位隐匿，检查困难，极易误诊而延误治疗。影像学检查中ＭＲＩ无假阴性报告，有助于本病的早期发现。

Chordoma is a rare neoplasm which arises from the mbryonic remnant of the noto-chord.The paper reported 24 cases of chordomas in the skull base. According to sythptoms,signs,imaging features,operation findings, the original places and the expansive directions of the tumor,they were divided into four clinical types:sellar,clival,occipito-temporal and extent. The choices of surgical approaches were suggested on these types. They are difficult to remove because of their deep site,limit operative field and close to the important vessels,nerves and brain,and they recur frequently after oper-ation.