摘要
研究了双光气染毒后不同时间大鼠支气管肺泡灌洗液(BALF)成分及肺形态学改变。结果表明,双光气染毒后,BALF成分的变化程度与肺形态改变密切相关BALF成分分析可作为动物实验中探测双光气所致肺损伤的有力手段。
he changes of
bronchoalveolar lavage fluid(BALF)components and pulmonary morphology were studied inrat
lungs at 6 h, 24 h,3 d, 10 d after a 20-minute exposure to diphosgene(44.9mg/m3).The results
indicated thatthere was good correlation between the degree of changes in BALF components and
the morphological alterationsin lung tissue.The analysis of BALF components provided a sensitive
method for determining subtle changes in thelung following diphosgene exposure in animal
experiments.
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
1994年第2期92-94,共3页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
双光气
肺损伤
支气管
肺泡
灌洗液
Diphosgene Lung damage BALF Morphological observation