髂内动脉化疗栓塞治疗盆腔晚期癌肿

Internal Iliac Arterial Chemo-embolization in the Treatment of Late Pelvic Cancer

对５８例进展期或复发性盆腔恶性肿瘤施行了双侧髂内动脉灌注化疗，并在灌注后分别用微球和明胶海绵碎块做了栓塞。绝大部分患者的出血、腹水、患部疼痛等症状得以缓解。微球组２１例显示完全有效（ＣＲ）２例，部分有效（ＰＲ）１３例，轻微有效（ＭＲ）５例，无效（ＮＣ）１例。１年生存率２８．６％（６／２１），半年生存率７６．２％（１６／２１）。化疗栓塞后并发症有下肢肌力减退和感觉异常，臀部疼痛和红斑等。除１例微球栓塞后出现下肢严重的运动和感觉障碍外，其余患者均在短期内恢复正常。明胶海绵栓塞后无严重并发症发生。

Transcatheter bilateral internal iliac arterial chemotherapy and embolization using microspheres or gelfoam fragment were performed in 58 patients with advanced or recurrent pelvic ma-lignant tumors;The clinical symptoms e.g. bleeding,ascites and local pain etc. of most patients were alleviated.In microsphere group including 2 1 cases the tumor showed complete response(CR ) to the therapy in two patients,partial response(PR)in 13, miner response(MR)in five, and in one,no changes(NC). The 1-year survival rate was 28.6%(6/21),the half-year survival rate was 76.2%(16/21).The important complications after chemo-embolization included lower limb paresthesia and weakness, pain and erythema of buttock etc.,but all recovered in short time except one case with severe lower limb motor and sensory disturbances who was embolized by microsphere。No severe complications occured after gelfoam embolization.