放置与未放置宫内节育器妇女异位妊娠285例临床病理分析

Clinico-pathologic study of 285 cases of ectopicpregnancy in intrauterine devices-users andnon-intrauterine devices-users

对１９９０年度北京市部分地区放置宫内节育器（ＩＵＤ）发生异位妊娠妇女１５０例（ＩＵＤ组），与未放置ＩＵＤ发生异位妊娠妇女１３５例（非ＩＵＤ组）的临床资料及病理组织学进行比较研究。询问及检查项目包括盆腔炎史，异位妊娠部位、侧别，输卵管炎症及非炎症病变类别，妊娠黄体侧别，子宫内膜组织类型等。同时利用图像分析仪，对其中５０例输卵管粘膜上皮表面纤毛长度及纤毛面数密度进行了形态学测试。各项检查分析结果表明：除卵巢妊娠率ＩＵＤ组明显高于非ＩＵＤ组外（Ｐ＜０．０５），其它结果，两组差异均无显著意义（Ｐ＞０．０５）。提示：ＩＵＤ组与非ＩＵＤ组输卵管粘膜上皮受损伤程度相似，证实ＩＵＤ不增加输卵管病变的危险性。

wo hundreds eighty five cases of ectopic preg-nancy in Beijing area from Jan. 1 to Dec.31 1990 in-cluding 150 cases of intrauterine devices (IUD) and135 cases of non-IUD users were studied.Clinico-pathological observation included the historyof pelvic inflammatory disease,the site of ectopicpregnancy,the classification of previous tubal in-flammation of the ectopic side and other pathologiclesions,the side of the comus luteum ofpregnancy andhistology of endometrium,etc. Besides,usingstereologic technique the cilia length and cilia densityof endosalpinx were studied in 50 cases through imageanalysis system. Results showed that except for a sig-nificant higher frequency of ovarian pregnancy inIUD-users,there was no significant differences be-tween the 2 groups.It indicated that the degree of in-jury of fallopian tubes and the factors causing thedamage were similar in both groups.The authors con-cluded that IUD does not increase the risk of fallopiantube lesions.