冠心病合并2型糖尿病的冠状动脉造影特点及支架置入术的疗效观察

Clinical analysis of coronary angiography and clinical efficacy of coronary stenting in coronary artery disease patients with type 2 diabetes

目的:分析冠心病合并2型糖尿病患者的冠状动脉造影结果,并评估冠脉内支架置入术的临床疗效。方法:比较206例冠心病合并糖尿病患者(A组)与492例无糖尿病冠心病患者(B组)的冠状动脉造影结果,并比较118例冠心病合并糖尿病患者(C组)与311例无糖尿病冠心病患者(D组)冠脉内支架置入术的疗效。结果:与无糖尿病冠心病相比,冠心病合并糖尿病的冠脉病变更复杂、更严重,外科冠状动脉旁路术多(36.89% vs 19.10%, P<0.05)。两组即刻手术成功率高(100%vs99.68%),前组无严重并发症发生。结论:冠心病合并糖尿病患者冠脉内支架置入术安全有效,能显著降低心脏不良事件发生率。

Objective: To analyze the clinical outcomes of coronary angiography and evaluate the clinical efficacy of coronary stenting in coronary artery disease patients with type 2 diabetes. Methods: Comparing with nondiabetics subjects(B group,n=492) , the clinical outcomes of coronary angiography in 206 patients with coronary artery disease and type 2 diabetes (A group) were analyzed. 118 diabetic patients (C group) and 311 nondiabetic patients(D group) were treated with bare metal stents. Baseline clinical characteristics, procedural success rate, occurrence of cardiac events were recorded and compared between C group and D group. Results:Comparing with B group, coronary artery lesion in A group was significantly serious and complicated, and those diabetic patients who underwent coronary artery bypass grafting were significantly more than nondiabetic patients(36. 89% vs 19. 10% , P <0.05). The procedural success rate was 100% in C group and 99. 68% in D group. Conclusion: Stent implantation for diabetic patients with coronary artery disease is safe and effective, and can reduce major adverse cardiac events.