动脉灌注灭活再植和体内切刮灭活治疗骨肉瘤的近期疗效观察

Observations of short Term Results of TwoKinds of Operations ’Devitalization and Replanta-tion after Local Arterial Perfusion or Intrinsic Re-section and Curettage with Devitalization in theTreatment of Osteogenic Sarcoma

本组１９例骨肉瘤患者分别采用动脉区域灌注灭活再植和体内切刮灭活手术治疗，术后平均两年存活率为８４．２％，与同期截肢组无显著性差异（Ｐ＞０．２５）。局部复发率为５．３％；两种保肢手术方法的两年存活率亦无显著性差异（Ｐ＞０．２５）。表明在化疗保障下，保肢与截肢手术在骨肉瘤的治疗中，可以获得相同的近期疗效。其中体内切刮灭活术具有简便、保留骨及关节原有形态及部分功能、并发症少和较经济的优点。

Abstract Devitalization and replantation after local arterial perfusion or intrinsic resection and curettagewith devitalization,the average postoperative twovear survival rate is 84.2%in 19 patients with os-teogenic sarcoma。 Cornpared with the 29 patientswho had amputation owing to osteogenic sarcomain same duration,there is no obvious difference inthe postoperative two-years survival rate(P>0.90,P>0. 25),and also no obvious differencebetween thetwo-vears survival rates of the twokinds of limb preserving surgery(P> 0. 25 Thelocal recurrence rate is in the order of 5.3% in thecases of limb preserving surgery。 It was shownthat the short term results is the same in the treat-ment of Osteogenic sarcorna by limb preservingsurgery or amputation,and there are some meritsin intrinsic resection andcurettage with devitaliza-tion,such as keeping the original contour and con-tinuity of bone and joint,retaining partial functionof the injured joint, performing easily ,less compli-cations and less expensive。