高频喷射通气对海水性肺损伤换气功能的影响

THE EFFECT OF HIGH-FREQUENCY JET VENTILATION ON PULMONARY GAS EXCHANGE SEA-WATER INSTILLATION DAMAGE

本文向绵羊肺内灌入海水造成急性肺损伤。随机分为高频喷射通气（ＨＦＪＶ）组（９只）和对照组（５只）。对两组ＰａＯ２、ＰａＣＯ２、肺泡－动脉氧分压差［Ｐ（Ａ－ａ）Ｏ２］及肺分流率（ＱＳ／ＱＴ）进行了动态观察。结果显示，ＨＦＪＶ组ＰａＯ２高于对照组，而ＱＳ／ＱＴ及Ｐ（Ａ－ａ）Ｏ２则低于对照组。作者认为，ＨＦＪＶ对改善肺泡换气功能，抢救海水溺水有一定作用。不断清除气道内泡沫状液体，保持气道通畅是ＨＦＪＶ治疗的前提；尽可能延长ＨＦＪＶ使用时间，效果可能更佳。

ea-water was instilled into the lungs of the sheep,resulting in acute pulmonary damege. The animals were randomly divided into two groups, one the high-frequency iet ventilation(HFJV) group(9 animals) and the other the control group(5 animals). Continuous observations of the PaO2,PaCO2,P(A-a)O2 and QS/QT were made, The results showed that PaO2 of the HFJV group was higher, whereas QS/QT and P(A-a) O2 were lower than those of the control group. These suggest that HFJV has positive ef- fects on improving the gas-exchange function of the pulmonary alveoli and can be used for emergency treatment of drowning subjects, The success or failure of HFJV treat-ment depends very much on the continuous clearing away of foamy liquid and the main-tenance of free air way. Prolonged HFJV may produce better results.