早产胎膜早破141例临床分析

Preterm premature rupture of membrane:clinical analysis of 141 cases

目的探讨早产胎膜早破(preterm premature rupture of membrane,PPROM)发生的危险因素及对母儿的影响.方法回顾性分析2001年1月至2004年6月在我院产科住院的早产胎膜早破的病例141例.结果74.47%的PPROM有易发因素存在,比较孕28～34+6周与孕35～36+6周的PPROM,发现其分娩方式差异无显著性(P＞0.05),但新生儿体重、从破膜到分娩时间的差异有显著性(P＜0.05).孕28～34+6周PPROM新生儿窒息、呼吸窘迫综合征(respiratory distress syndrome,RDS)发生率和死亡率明显高于孕35～36+6周者.结论对于孕28～34+6周者宜采用期待疗法,以减少新生儿并发症的发生.

Aim To study the high risk factors of preterm premature rupture of membrane (PPROM) and related factors of affecting maternal and preterm infants.Methods A retrospective review was made of one hundred and fourty-one cases of PPROM between Jan.2001 and Jun.2004 in the Fourth People's Hospital of Tongling. Results 74.47 percent cases had high risk factors of PPROM. A comparison of 28~34~ +6 weeks with 35~36~ +6 weeks shows the labour styles were insignificant,but the weight of infants and duration from premature rupture of membrane to delivery had significant difference. 28~34~ +6 weeks had higher neonatal asphyxia and neonate respiratory distress syndrome( RDS) rates than 35~36~ +6 weeks. In addition ,more death in 28~34~ +6 weeks~ . Conclusion To reduce neonatal complications we must take expectation treatments to prolong pregnant period in 28~34~ +6 weeks of PPROM.