前列腺素E_1结合舒血宁治疗缺血性脑梗死的疗效观察(附156例报告)

Observation of therapeutic effect of ischemic cerebrum infarction tre ated with prostin E_1 and combined with Shu Xue Ning (Report of attached 156 cases)

目的探讨前列腺素E1结合舒血宁治疗缺血性脑梗死的临床疗效及安全性。方法156例缺血性脑梗死患者随机分成观察组和对照组,两组基础治疗相同,观察组在此基础上加用前列腺素E110μg,舒血宁注射液20mL,两组在治疗前后均进行神经功能缺损程度评分及血液流变学检查。结果前列腺素El结合舒血宁能减少脑梗死患者神经功能缺损程度评分及血液流变学的变化;治疗缺血性脑梗死有效率为90.52%;对照组有效率为67.13%,两组相比差异有显著性(P<0.05)。结论前列腺素E1结合舒血宁能减少缺血性脑梗死患者神经功能缺损程度评分,治疗缺血性脑梗死有效。

[Objective] To study the clinic effect and safety of Ischemic Cerebr um Infarction treated with Prostin E1 and Combined with Shu Xue Ning. [Methods ] 156 patients with Ischemic Cerebrum Infarction were randomly divided into tes t group and control group. The basic treatments of two groups were identical. Ba sed on the basic treatments, the test group was treated with Prostin E1 10 μg a nd Shu Xue Ning injection 20 mL. The loss level on nerve function were marked an d the changes of blood flowing were examined in two groups before and after trea tment. [Results] The therapy of Ischemic Cerebrum Infarction treated with Pros tin E1 and Combined with Shu Xue Ning could decreased the loss level of nerve fu nction and the changes of blood flowing. The effective therapy rate of Ischemic Cerebrum Infarction was 90.52%. The effective rate of the control group was 67.1 3%. There was significantly statistical difference between two groups(P<0.05). [Conclusions] The therapy of ischemic cerebrum infarction treated with Prostin E1 and combined with Shu Xue Ning can decreased the loss level on nerve functio n and the changes of blood flowing and is effective.