膳食中蛋白质比例对小鼠加速度耐受性的影响

Effects of dietary protein content on +Gz tolerance in mice

为探讨膳食中不同热源质比例与机体加速度耐受性的关系，观察了增加膳食中蛋白质比例对小鼠加速度耐受性的影响。将300只体重15～20巴雄性小鼠随机分为3组，每组100只。A组饲喂高蛋白质膳食（蛋白质热比47.6％），B组饲喂较高蛋白质膳食（蛋白质热比31．1％），C组饲喂适量蛋白质膳食（蛋白质热比15．0％）。饲养3周后分别从各组随机抽取小鼠60只暴露于+16Gz10min，另取20只暴露于+20Gz10min，记录死亡数，计算死亡率。另从各组未经+Gz暴露的动物中分别随机抽取12只测定总运动次数；再从各组暴露于+16Gz10min后存活的动物中分别随机抽取12只，于+Gz暴露后30min内测定总运动次数。结果表明，暴露于+16Gz10min的各组动物死亡率有随膳食中蛋白质比例增加而降低的趋势，膳食中蛋白质比例增加的小鼠+Gz暴露后30min内的总运动次数多于不增加者；暴露于+20Gz10min时三组小鼠死亡率无明显差别。饲养期间，膳食中蛋白质比例增加的小鼠生长较缓慢。结果揭示增加膳食中蛋白质比例对提高机体加速度耐受性有一定作用。

To explore the relationship between protein content in diet and Gz tolerance, 300 micewere randomly divided into 3 groups to which diet of different protein cohtent was given: 47. 6% of pro-tein by calorigenic value (high protein feed) in group A, 31. 1 % (moderate high protein feed)in group Band 15. 0% (ordinary basic feed) in group C. After being on the given diet fOr 3 weeks,60 mice ran-domly taken from each group were exposed to +16 Gz and 20 mice exposed to +20 Gz for 10 min. Mor-talities after exposure were counted,and movements of mice in 30 min following +Gz exposure recordedand compared with those of unexposed mice. The results showed that, in mice exposed to + 16 Gz therewas a tendency that the higher the protein content in diet the lower the mortality and the more move-ments recorded in 30 min after exposure,In mice exposed to +20 Gz the difference of mortalities among3 groups was non-significant. It was also found that the growth of body weight in mice on high proteindiet was significantly less than those on basic diet.