颈、胸段食管癌术后的核素胃排空检查

RADIONUCLIDE GASTRIC EMPTYING TIME STUDY FOR PATIENTS WITH CERVICAL AND THORACIC ESOPHAGEAL CANCER AFTER RESECTION

用核医学方法测定胃排空具有无创伤性、可重复和定量的优点．我们用蛋黄糕干粉、水加９９ｍＴｃ－ＤＴＰＡ制成实验餐，对２４例健康人和７０例食管癌术后病人（胃代食道组２８例、结肠代食道组１４例、胸段食管癌术后组２８例）进行了核素胃排空研究．结果表明，胃代食道组胃排空较正常对照明显加快（Ｐ＜０．０１），结肠代食道组（卧位）和胸段食管癌术后组胃排空较正常组明显延迟（Ｐ＜０．０１）．而过快或延迟的胃排空都说明食管癌术后即使在３年以上，胃排空功能均受到一定程度的损害．

Abstract Semi-solid meal was mixed with 99mTc-DTPA and used as test meal given to patients orally. Gastric emptying time was measured in 70 patients after resection of esophageal cancer and 24 normal subjects. 70 patients were divided into 3 groups: (1) 14 cases with cervical esophageal cancer operated by using colon to replace the esophagus (CRE group).(2) 28 cases with cervical esophageal cancer operated by using stomach to replace the esophagus (SRE group). (3) 28 patients with thoracic esophageal cancer after resection only (TE group). The range of gastric emptying time of normal subjects was 53.9±10.5% / 60 minutes. Our results showed that SRE group (28 pts) had a more rapid gastric emptying time than that of normal subjects. CRE group (14 pts) and TE group (28 pts) had slower gastric emptying time than that of normal subjects.