营养性脑软化症雏鸡血浆TXB_2和6-keto-PGF_(1α)含量变化的研究

The plasma level of TXB_2 and 6-keto-PGF_(1α) in chicken with nutritional encephalomalacia

用放免测定法研究脑软化症患雏血浆中血栓素B(2TXB2)和6-酮-前列腺素(6-keto-PGF1α)含量,分析了TXB2/6-keto-PGF1α比值(T/P)的动态变化。结果发现,患雏血浆TXB2和6-keto-PGF1α含量及T/P比值较健康对照组显著增高(P<0.01)。表明TXB2、6-keto-PGF1α的含量变化及T/P值在雏鸡脑软化症的发生发展过程中起重要作用。

The development plasma levels of thromboxaneB2(TXB2)and 6-keto- prostaglandin( 6-keto-PGF1α)in chicken with nutritional encephalomalacia(NE)were measured by RIA and T/P was calculated. The results showed that the plasma level of TXB2 and 6-keto-PGF1α and T/P in ataxic chicks were significantly higher than that of healthy ones. The results indicate that level of plasma TXB2 and 6-keto-PGF1α and T/P have significant effect on the development of NE.