多发性硬化MRI诊断(附22例报告)

MRI Diagnosis of Multiple Sclerosis

目的：提高对多发性硬化（MS）MRI特征的认识。材料与方法：对22例MS患者行脑和／或脊髓MRI检查，对病变的分布、形态及病变的强化进行评价。结果：脑内病变位于侧脑室周围、半卵圆中心及脑干，室旁病变其长轴多于侧脑室垂直；脊髓病变多位于颈髓及上段胸髓，呈长条状。病变急性期及活动期强化，稳定期或斑痕期不强化。结论：MRI可显示MS的特征性表现，增强扫描可提高MRI对MS早期诊断的特异性，并能对MS的病理、生理特点进行时间顺序方面的观察。

Purpose:To get a better understanding of the characteristic MR apperance of MS lesions. Materi-als and methods: 22 MS patients underwent MR examination. The locations,shapes and apperance of the lesions be-fore and after injection of Gd DTPA were analysed. Results: The cerebral leslons were mainly located arround thelateral ventricles,in the centrum semiovals and the brain stem,the long axes of the periventricular lesions were per-pendicular to the lateral ventricles;The spinal lesions were mainly located in the cervlcal and upper thoracic cord,shaped as long strips. The actue and active lesions can be enhanced while the stable and scared lesions can not. Con-clusion :MR is capable of dernonstrating the characteristic apperance of MS lesions,thus enables us early diagnosisof MS.It also offers serial visualization of the lesions according to their pathophysiologic charateristics.