摘要
肿瘤的发生和发展是多基因参与的复杂生物学过程.从总体水平鉴定细胞癌变过程中异常变化的基因/蛋白质群,有助于全面认识肿瘤的生物学行为,同时也为寻找到有价值的肿瘤早期诊断标志物和治疗分子靶标开辟了新的途径.本文对近年来有关胰腺癌基因/蛋白表达谱的研究作一综述.
出处
《胰腺病学》
2005年第2期120-122,共3页
Chinese JOurnal of Pancreatology
基金
国家自然科学基金(30240050)
参考文献16
-
1Argani P. lacobuzio-Donahue C, Ryu B, et al. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin Cancer Res,2001,7: 3862-3868.
-
2Argani P, Rosty C, Reiter RE, et al. Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma.Cancer Res, 2001, 61 : 4320-4324.
-
3Rosty C, Ueki T, Argani P, et al. Overexpression of S100A4 in pancreatic duetal adenocarcinomas is associated with poor differentiation and DNA hypomethylation. Am J Pathol, 2002,160: 45-50.
-
4Li Z, Sclabas GM, Peng B, et al. Overexpression of synuclein-gamma in pancreatic adenocarcinoma. Cancer, 2004, 101 : 58-65.
-
5Crnogorac-Jurcevic T, Missiaglia E, Blaveri E, et al. Molecular alterations in pancreatic carcinoma : expression profiling shows that dysregulated expression of S100 genes is highly prevalent.J Pathol, 2003, 201: 63-74.
-
6Iacobuzio-Donahue CA, Maitra A, Olsen M, et al. Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Am J Pathol, 2003, 162 :1151-1162.
-
7Grutzmann R, Foerder M, Alldinger I, et al. Gene expression profiles of microdissected pancreatic duetal adenocarcinoma. Virchows Arch, 2003, 443: 508-517.
-
8Grutzmann R, Luttges J, Sipos B, et al. ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma. Br J Cancer, 2004,90:1053—1058.
-
9Iacobuzio Donahue CA, Ashfaq R, Maitra A, et al. Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. Cancer Res, 2003, 63: 8614-8622.
-
10Tanaka H, Hata F, Nishimori H, et al. Differential gene expression screening between parental and highly metastatic pancreatic cancer variants using a DNA microarray. J Exp Clin Cancer Res, 2003, 22: 307-313.
同被引文献8
-
1陈志荣,李兆申,屠振兴,龚燕芳,金晶,满晓华.胰腺癌组织中SMO mRNA的表达及其临床意义[J].胰腺病学,2005,5(2):82-84. 被引量:4
-
2汪丽娅,骆平,郭琪,陈志刚,雷益.2D-thick-TSE和2D-thin-HASTE MRCP技术的临床诊断比较[J].中国CT和MRI杂志,2005,3(3):44-45. 被引量:9
-
3陈灏珠.实用内科学[M](第10版)[M].北京:人民卫生出版社,1999.1138-1141.
-
4Foutch PC.Diagnosis of cancer by cytologic methods performedduring ERCP[J].Gastrointest Endosc,1994,40:249 ~ 252.
-
5周国雄,李兆申,许国铭,孙振兴,屠振兴,刘枫.内镜下胰腺细胞学检查方法对胰腺肿瘤的诊断价值[J].中国实用内科杂志,2002,22(11):659-660. 被引量:1
-
6林晓珠,陈克敏.CT灌注成像测量正常胰腺组织血流灌注[J].中国CT和MRI杂志,2004,2(1):29-32. 被引量:26
-
7王廷昱,陈晶,陈奋,陈大和,陈旭,冯远德.螺旋CT在急性胰腺炎诊断中的应用价值[J].中国CT和MRI杂志,2004,2(2):39-42. 被引量:25
-
8高军,李基根,周全,成官迅.中晚期胰腺癌的MRI诊断[J].中国CT和MRI杂志,2004,2(2):43-45. 被引量:13
-
1邵建文.肝脏血管平滑肌脂肪瘤的CT诊断[J].牡丹江医学院学报,2008,29(5):45-46.
-
2朱小朝,王勇,张拓,范卫东.血清CEA水平与结直肠癌发生部位的关系[J].南通大学学报(医学版),2016,36(5):487-488. 被引量:1
-
3肖家和.肿瘤的脑(脊)膜转移及其CT、MRI诊断价值[J].国外医学(临床放射学分册),1998,21(5):284-287. 被引量:3
-
4刘新杰,何文亮,麦沛成.乳腺癌腋窝淋巴结转移的临床意义[J].中国医师杂志,2003,5(5):715-716. 被引量:1
-
5叶敏.重视前列腺癌根治术中切缘阳性的问题[J].中华泌尿外科杂志,2004,25(8):509-511.
-
6章卫东,陈新龙,刘庆猛.后肾腺瘤1例报告[J].浙江实用医学,2011,16(1):75-76.
-
7石景森,郑见宝.进一步提高胆囊癌诊治的总体水平[J].临床肝胆病杂志,2013,29(6):401-403. 被引量:10
-
8王红霞,陈昊,闫蓉,张昶,徐宏志.涎腺癌组织中EGFR和HER-2表达及临床意义[J].临床与实验病理学杂志,2014,30(8):900-904. 被引量:6
-
9张建云,李树峰,徐峰.不同HER2表达情况下乳腺癌患者甲状腺激素与Ki67的相关性[J].山西医科大学学报,2015,46(11):1132-1135. 被引量:5
-
10杨旭红,张丽荣.208例宫颈癌的病理分析及p16和Ki67的表达[J].吉林医学,2016,37(4):831-832. 被引量:3