摘要
报道了266名汉族健康人腰椎、股骨上端骨密度(BMD)的随龄变化及其与性别、年龄、体重的关系以及80岁以上老年人血生化、性激素与BMD的关系。结果表明:男性随增龄股骨颈、股骨三角(Ward三角)及股骨粗隆BMD逐渐减低,腰椎(L2~L4)BMD变化不明显;而女性L2~L4、股骨颈、Ward三角、股骨粗隆的BMD随增龄均逐渐减低。全部受检者不分性别,其BMD丢失速度:Ward三角>股骨粗隆>股骨颈>L2~L4。各测定部位间BMD相关良好,BMD与年龄呈负相关,与体重呈正相关。80岁以上老年人BMD与血清睾酮水平呈正相关,与血清磷和碱性磷酸酶呈负相关,与血清钙和雌二醇呈弱的正相关。
Abstract Bone mineral density(BMD) changes of the lumbar vertebral and the upper part of femur in 266 normal subjects of Han nationality in relation to aging process were reported. The relationship between the BMD changes and some palameters such as sex,age,body weight,blood biochemistry and sex hormone level was studied.It is shown that in male subjects BMD of the femoral neck,triangle(ward's triangle) and trochanters decreased with aging,but that of 2nd to 4th lumbar vertebral did not.On the contrary,in female subjects BMD decreased not only in different parts of femur,but also in tbe lumbar ventebral.In both sexes the speed of BMD changes in different parts of the bones was in such an order:Ward's tringle>trochanters>neck>lumbar vertebral.The relation between BMD changes and aging was obvious.BMD was correlated negatively with aging and positively with body weight.In subjects aged over 80,BMD was correlated positively with the blood level of testosterone and hegatively with that of phosphorus and alkaline phosphatase,but it was only weakly correlated with the blood level of calcium and estradiol.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1994年第6期323-326,共4页
Chinese Journal of Geriatrics