摘要
本文对孕妇血、新生儿脐血和2月龄婴儿血中脊灰三型中和杭体垂直分布情况进行研究。结果表明:孕妇血中脊灰三型抗体阳性率在92.5%以上;GMT在14.58~32.67之间;Ⅰ、Ⅱ型阳性率、GMT基本一致,Ⅲ型较低,新生儿脐血比该孕妇血中GMT低50%左右,2月龄婴儿血脊灰三型抗体阳性率和GMT均低于母血和新生儿脐血中脊灰抗体阳性率和GMT;2月龄婴儿脊灰单型抗体阴转率达64.1%~83.87%,三个型别抗体均阴转者达44.8%,与生母及新生儿脐血中和抗体水平呈明显负相关,表明婴儿出生后至2个月初次免疫前,确实存在着免疫裂隙,建议推行新生儿“0”次接种或孕妇第28周开始服OPV。
study on antibody distribution and titer aga-inst poliovirus in 67 mothers and their 60-day-old new-born babies was carried out in Shi-yan, Hubei Province. The positive rates andthe geometric mean titers of antibodies aga-inst Types Ⅰ-Ⅲ poliovirus in mnothers were98.58%,1 : 32.67; 95.5%,1: 30.07; 92.5%,1:14.58,respectively.In their 60-day-old babies,theantibody positive rates and geometric meantiters fell obvionsly; they were 34.3%,1:2.45:34.3%,1:2.22; and 14.9%,1:1.34, respectiv-ely. The authors suggest to immune those neo-nates(OPV zero),or to immune those moth-ers beginning from 28 weeks of pregnancy inorder to raise the antibody titer and protecttheir babies during the early days.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
1994年第3期158-161,共4页
Chinese Journal of Epidemiology