中老年人髂骨骨形态计量参数的比较

A comparison of the parameters of iliac bone histomorphometry between the middle-age and the aged

测量３７例健康中老年人的髂骨标本，并计算了有关髂骨形态计量的多项参数。其中，老年组骨小梁骨体积占全部骨髓腔体积的百分比为１７．７土６．０％，中年组为２７．４土５．０％（Ｐ＜０．０１）；平均骨小梁板密度两组分别为１．３±０．４／ｍｍ和１．８±０．３／ｍｍ（Ｐ＜０．０１）；平均骨小梁板间隙两组分别为６８０．７±２１７．４μｍ和４２０．０±８８．７μｍ（Ｐ＜０．０１）。且在不同性别的中老年人比较中，以上参数的差异均有显著性。我们认为，上述三项指标是研究老年性骨质疏松的重要的骨形态计量学参数。

Abstract A study of iliac specimens was performed in 37 middle-age and aged healthy subjects.The plate parameters measured and calculated aredescribed as follows:trabecular bone volume(TBV),mean trabecular thickness(MTPT),mean trabecular plate density(MTPD),mean trabecular plate spacing(MTPS),trabecular osteoid surface over total trabecular bone surface(TOS/TBS) and cortical bone width(CBW).It is noteworthy that significant differences were found in TBV,MTPD and MTPS between the two age groups.However,no significant difference was noted in TOS/TBS,EOS/EBS and CBW.We conclude that aging may exert obvious effects on bone microarchitecture and the Parameters,such as TBV,MTPD and MTPS,can be used to investigate senile osteoporosis.