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运动训练对老年小鼠巨噬细胞功能的影响 被引量:1

Experimental research on macrophage function in trained aged mice
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摘要 对游泳训练三个月的C57BL/6老年小鼠巨噬细胞功能进行了研究。结果是老年鼠不运动组巨噬细胞的吞噬和抑瘤功能较青年鼠降低;老年鼠运动组巨噬细胞白细胞介素1(IL-1)分泌、吞噬和抑瘤功能均较不运动组增强(P<0.001)。表明适量运动训练可增强巨噬细胞功能,而起到一定的抗衰老作用。 Abstract The present study was designed to examine the functions of the Peritoneal macrophage of the swimtrained aged C57BL/6 mice(PMM).The functions of the PMM in the young controls were also studied.Phagocytic activity and tumor-cytostatic activity of the PMM in the aged controls(not trained) were lower than that in the young controls.IL-l production,phagocytic activity and tumor-cytostatic activity of the PMM in the trained aged mice were all higher than those in the aged controls.The results showed that moderate exercise training may promote the macrophage function in the aged;this would be beneficial in Preventing the occurrence of some diseases and delaying the Process of aging.
出处 《中华老年医学杂志》 CAS CSCD 北大核心 1994年第6期346-347,共2页 Chinese Journal of Geriatrics
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  • 1张惠华,中国免疫学杂志,1989年,5卷,75页

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