经皮自体骨髓移植治疗胫骨不连的临床研究

Percutaneous Autogenous Bone Marrow Grafting for Management of Nonunin of Tibia Fractures

目的 研究经皮自体骨髓移植治疗胫骨不连的疗效。方法 治疗组 17例与对照组 13例作对比分析。操作在严格无菌局麻下进行。在X光电视监视下 ,将一枚骨穿针穿入骨不连部位 ,然后抽取自体髂骨红骨髓并立即注入胫骨不连部位 ,一次注入约 2 0～ 4 0ml,注射后患肢应给予有效的固定。 3周一次 ,注射 2～ 3次。结果 16例胫骨不连患者获得愈合 ,骨折愈合率 96 .1% ,平均愈合时间 7.5个月。结论 经皮自体骨髓移植在胫骨不连部位有成骨作用 。

Objective To study the effect of percutaneous autogenous bone marrow grafting in the management of nonunion of tibia fractures.Methods Seventeen patients in the treatment group were treated for nonunion of tibia fractures.The operation was performed under local anesthesia.A marrow needle was inserted into the site of nonunion under the X-ray,and a total of 20～40ml of bone marrow was aspirated from the anterior or posterior iliac crest and was injected immediately into the site of nonunion.The limb was then immobilized.The procedure was repeated at 3 weeks for 2～3 times.13 patients were served as the control group.Results Sixteen cases of seventeen tibia fractures had union in 5～10 months.The rate of bony union was 96.1%,with an average healing time of 7.5 months.Conclusion Percutaneous autogenous bone marrow grafting can play a role in osteogenesis at the site of nonunion.This method is valuable for the treatment of nonunion of tibia fractures.