3种预防顺铂所致呕吐方案的成本-效果分析

Cost-effectiveness Analysis of Three Preventing Schemes for Cisplation-induced Vomiting

目的 探讨不同药物治疗方案用于同一疾病所产生的经济效果。方法 顺铂化疗患者 2 0 2例随机分为 3组 ,分别给予舒必利、恩丹西酮和甲氧氯普胺进行预防呕吐治疗 ,运用药物经济学的成本 -效果分析方法进行评价。结果 3种治疗方案中 ,舒必利方案有效率为 87.1% ,1个疗程费用为 93.3元 ,有效率每增加 1个百分点 ,成本为 1.0 7元 ;恩丹西酮方案有效率为 93.5 % ,1个疗程费用为 4 4 8.2 6元 ,有效率为每增加 1个百分点 ,成本为 4 .79元 ;甲氧氯普胺方案有效率为 5 7.5 % ,1个疗程费用5 4 .33元 ,有效率每增加 1个百分点 ,成本为 0 .94元。结论 舒必利方案是

Objective To discuss the economic effects of different therapeutic schemes in the treatment of the same illness.Methods 202 cases receiving cisplatin chemotherapy were randomly divided into three groups according to preventing schemes received:Group 1,sulpiride;Group 2,ondansetron and Group 3,metoclopramide.Data was evaluated using pharmacoeconomic cost-effectiveeness analysis.Results The effective rate of sulpiride was 87.1%, The expense of one course of treatment being 93.3yuan and the increasing of 1% effective rate cost 1.07 yuan.The effective rate of ondansetron was 93.5%, the expense of one course of treatment being 448.26 yuan and the increasing of 1% effective rate cost 4.79 yuan.The effective rate of metoclopramide was 57.5%,the expense of one course of treatment being 54.33 yuanand the increasing of 1% effective rate cost 0.94 yuan.Conclusion The sulpiride scheme is the more rational one.