产程中应用杜冷丁对产程及新生儿的影响

Effects of Applying Pethidine on Birth Process and Newborn Infants

目的 观察杜冷丁对产程及新生儿的影响。方法 将 16 0例初产妇随机分为观察组和对照组 ,各 80例 ,观察组在宫口开大 1.2cm时杜冷丁 10 0mg肌肉注射 ,对照组未用药。结果 第一产程用药组与对照组相比明显缩短 ,有显著差异 (P <0 .0 5 ) ,第二、三产程无差异 (P >0 .0 5 ) ,对新生儿影响、产后 2小时内出血量及新生儿体重两组无差异 (P >0 .0 5 )。结论 产程中应用杜冷丁可减轻产妇疼痛 ,缩短第一产程 ,不增加新生儿窒息 。

Objective To investigate the effects of pethidine on stages of labor and newborn infants. Methods 160 pregnant women were randomly divided into the treatment group (pethidine, 100mg im) and the control group. Results The time of the first stage of labor in the treatment group was 352.41±21.51 minutes, while in the control group it was 472.00±33.79 minutes (P<0.05); the time of the second stage of labor in two groups was 60.44±4.59 minutesand 66.71±4.47 minutes respectively (P>0.05); the time of the third stage of labor was 5.64±0.44 minutes and 6.18±0.59 minutes (P>0.05). Its effects on newborn infants and the volume of bleeding after 2 hours' labor were not significant (P>0.05). Conclusion To apply pethidine in birth process can relieve the parturients'pain,reduce the first stage of labor and not increase the possibility of newborninfants' asphyxia.