小儿氨茶碱中毒的药理及临床防治

Pharmocology of Infant Aminophylline Poisoning and ItsPrevention and Treatment

目的 氨茶硷是临床上常用的止喘药物 ,但儿科用药剂量应严格控制 ,以防中毒。方法 本文根据 1996年～ 2 0 0 0年出院的病案中 ,抽完整的病例资料 8例 ,在临床上应用氨茶硷中毒的小儿合并消化道出血 ,经统计学处理分析 ,呈正相关。结果 表明超剂量应用氨茶碱并同时应用异丙嗪药物 ,致消化道出血症状加重 ,有显著差异性。结论 文章对氨茶碱中毒的临床表现及预防等问题进行了分析讨论 。

Objective Aminophylline is clinically used as a common antasthmatic, but the pediatric dosage should be strictlycontrolled in order to prevent poisoning.Methods 8 aminophylline poisoning cases with hemorrhage of digestive tract were selected from the discharged cases with hemorrhage cases from 1996 to 2000, andanalyzed according to statistics (being positive correlation). Results Excess dosage of aminophylline together with phenergan could make the symptoms of hemorrhage digestive tract more severe.There was a significant difference.Conclusion Clinical manifestations of aminophylline poisoning should be carefully observed in order that aminophylline might be used better clinically.