紫外线红斑治疗皮下瘀血的机理研究

Mechanism of Ultraviolet Erythema on Subcutaneous Ecchymosis

红斑量紫外线照射皮下瘀血斑１０例，照射后２．５～１２．０小时红斑区瘀血斑完全消除。观察２３例骨质增生性疾病患者表明，局部紫外线照射后１小时，血浆纤维蛋白原（ＢＰＦ）含量明显降低（Ｐ＜０．０１）．１２例皮下瘀血患者应用纤溶抑制剂后照射紫外线，ＢＰＦ含量不再降低，但皮下瘀血依然显著吸收．实验证明，红斑量紫外线局部照射能激活纤维蛋白溶解系统活性，但紫外线消除皮下瘀血的作用与此无明显关系，而主要与其局部红斑反应有关．

In this paper,we performed some experiments to study the mechanism of ultraviolet erytheme on subcutaneous ecchymosis.10 cases with traumatic subcutaneous ecchymosis were only radiated with ultraviolet erythema (2-3 MED)one the, the ecchymosis disappeared completely at 2.5-12 hours of post-radiation. In order to explore the relation between fibrinolysis and ultraviolet erythema, the plasma fibrinogen level of 23 cases with osteoarthropathy which were radiated with ultraviolet 1 hr was measured.The plasma fibrinogen content was obviously decreased(P<0.01).Another 12 cases with subcutaneous ecchymosis were first administered ths fibrinolytic inhibitor,then the ultraviolet erythema was given.In the treatment,although the level of fibrinogen didn't decrease,the ecchymosis was also absorbed remarkably. The experiment demonstrates that the ultraviolet erythema radiation may enhance the activity of fibrinolytic system,but its effective mechanism was mainly related to local erythema reaction.